5-Amino-1MQ
Metabolic Research only Animal studies
Also called 5-amino-1-methylquinolinium, NNMTi
Not a peptide — a small molecule that blocks NNMT, an enzyme fat cells use to burn through their nicotinamide supply. Blocking it raises cellular NAD+ and, in mice, made fat cells shed stored fat without any change in diet.
Why people take it
What studies report
- Reduced fat mass in diet-induced obese mice while food intake stayed the same
- Higher NAD+ and SAM levels in cultured fat cells
- Promoted muscle stem cell proliferation in culture
In practice Unapproved use
- Taken orally in capsules, usually in 4–8 week blocks
- Marketed and used for fat loss without appetite suppression
- Often stacked with MOTS-c and NAD+ precursors
Science hasn't caught up: Sold widely as an oral fat-loss supplement on the strength of mouse data alone.
Reported real-world use, not evidence and not a recommendation.
Worth knowing: Mouse and cell-culture data only, and no human trial has been published. Oral bioavailability in people is unestablished.
Status: Research compound. Not approved.
- Route
- Oral capsule — a small molecule, so digestion is not a barrier
- Formula
- C10H11IN2
- Molecular weight
- 286.11 g/mol
- CAS
- 42464-96-0
- Available as
- 10 mg
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.