BPC-157

Healing & repair Research only Animal studies

Also called Body Protection Compound 157

A 15-amino-acid synthetic peptide based on a protein fragment found in stomach juice. In animal studies it has been linked to faster healing of tendon, muscle, gut and skin injuries, new blood vessel growth, and effects on nitric oxide signaling.

Why people take it

Achilles and other tendon tearsACL and meniscus injuryRotator cuff tearsIT band syndromeGut lining, GERD and ulcersTendon, ligament and muscle injury

What studies report

Faster tendon, ligament and muscle healing in rat injury models
Protection of the stomach and gut lining against NSAID and alcohol damage in rodents
New blood vessel growth at injury sites in animals

How it works

Derived from a protein in gastric juice. Reported to upregulate growth hormone receptors via the phospholipase C pathway and to drive angiogenesis — new blood vessel growth into damaged tissue.

In practice Unapproved use

Among the most widely used peptides in the injury-recovery community, usually run in 4–8 week blocks
Commonly injected near the injury site for tendon and ligament problems, or systemically
Oral and capsule forms are preferred for gut complaints, since it originates in the digestive tract
Routinely stacked with TB-500 — the pairing is common enough to have its own nickname

Science hasn't caught up: This is the widest practice-versus-evidence gap in the library: near-universal adoption in recovery circles, zero published controlled human trials.

Reported real-world use, not evidence and not a recommendation.

Worth knowing: Essentially all of this is rodent data. There are no published controlled human trials, and claims about joint or gut healing in people are extrapolation.

Status: Evidence is almost entirely from animal and cell studies. Human data are very limited. Not approved.

Route: Subcutaneous injection; oral and capsule forms are used for gut complaints
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Formula: C62H98N16O22
Molecular weight: 1419.5 g/mol
CAS: 137525-51-0
Available as: 10 mg

View on PubChem →

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.