CJC-1295 without DAC

Growth hormone Research only Human trials

Also called Modified GRF (1-29), Mod GRF, Tetrasubstituted GRF (1-29)

A 29-amino-acid version of growth-hormone-releasing hormone (GHRH) with four amino acids swapped to make it harder to break down. It signals the pituitary to release growth hormone in pulses. 'Without DAC' means it lacks the add-on that gives the DAC version a multi-day half-life.

Why people take it

Lean muscle preservationFat lossTissue repairSleep qualityGrowth hormone releaseBody composition

What studies report

Pulses of growth hormone release in human pharmacology studies
Raised IGF-1 in combination studies with ghrelin-receptor peptides

How it works

Binds pituitary GHRH receptors to stimulate the body's own pulsatile growth hormone release, leaving normal feedback control intact.

In practice Unapproved use

Almost always paired with ipamorelin rather than used alone
Taken before bed to align with natural growth hormone release
Often run five days on, two off

Reported real-world use, not evidence and not a recommendation.

Worth knowing: Studied for hormone response, not for outcomes like body composition or recovery.

Status: Research compound. Not approved.

Route: Subcutaneous injection, from reconstituted lyophilised powder
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Formula: C152H252N44O42
Molecular weight: 3367.9 g/mol
CAS: 863288-34-0
Available as: 5 mg

View on PubChem →

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.