DSIP
Sleep Research only Human trials
Also called Delta sleep-inducing peptide, Emideltide
A nine-amino-acid peptide first isolated in the 1970s from rabbits in deep sleep. Beyond sleep patterns, it has been studied for effects on stress hormones, pain perception and blood pressure. Results across studies are mixed, and how it works is still unclear.
Why people take it
What studies report
- Shorter time to fall asleep and better sleep quality in small older studies of poor sleepers
- Reduced reported pain in a small chronic pain study
- Changes in cortisol and growth hormone release
In practice Unapproved use
- Used intermittently before bed rather than nightly
- Results are inconsistent enough that the community is openly divided on whether it works
Reported real-world use, not evidence and not a recommendation.
Worth knowing: Human studies are from the 1980s-90s, small, and inconsistent; several found no effect.
Status: Small, older human studies. Not approved.
- Route
- Subcutaneous injection, from reconstituted lyophilised powder
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
- Formula
- C35H48N10O15
- Molecular weight
- 848.8 g/mol
- CAS
- 62568-57-4
- Available as
- 5 mg
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.