Kisspeptin-10
Hormonal Research only Human trials
Also called Kp-10, Metastin (45-54)
The shortest fully active fragment of kisspeptin, the brain signal that starts the reproductive hormone cascade. It triggers GnRH release, which in turn raises LH, FSH and sex hormones. It is studied in fertility treatment and low-testosterone states. The parent protein was first found as a suppressor of cancer spread.
Why people take it
What studies report
- Triggers LH and testosterone release in healthy men
- Used in fertility research to mature eggs with less risk of ovarian hyperstimulation
- Increased brain responses to sexual and emotional cues in imaging studies
In practice Unapproved use
- Used in fertility and TRT-adjacent circles to support the body's own hormone signalling
Reported real-world use, not evidence and not a recommendation.
Worth knowing: Human studies are short single-dose experiments, not treatment courses.
Status: Used in human research studies. Not approved.
- Route
- Subcutaneous injection, from reconstituted lyophilised powder
- Sequence
- Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
- Formula
- C63H83N17O14
- Molecular weight
- 1302.4 g/mol
- CAS
- 374675-21-5
- Available as
- 3 mg
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.