KPV
Immune Research only Animal studies
Also called α-MSH (11-13)
The last three amino acids of alpha-melanocyte-stimulating hormone. It keeps much of that hormone's anti-inflammatory activity without causing skin darkening. It is studied mainly for gut inflammation such as colitis, and for skin inflammation.
Why people take it
What studies report
- Reduced colitis severity in mouse models, including when given orally
- Anti-inflammatory effects in skin, gut and joint models
- Keeps the anti-inflammatory action of alpha-MSH without skin darkening
In practice Unapproved use
- Taken orally in capsules for gut inflammation
- Applied topically for inflammatory skin conditions
- Popular in the inflammatory bowel community
Reported real-world use, not evidence and not a recommendation.
Worth knowing: Animal and cell data only.
Status: Animal and cell research only.
- Route
- Oral capsule or topical; occasionally injected
- Sequence
- Lys-Pro-Val
- Formula
- C16H30N4O4
- Molecular weight
- 342.43 g/mol
- CAS
- 67727-97-3
- Available as
- 10 mg
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.