Thymosin-β4 Fragment 1-4

Healing & repair Research only Animal studies

Also called Ac-SDKP, Seraspenide

The first four amino acids of thymosin-β4, which the body clips off naturally. This fragment carries much of the parent peptide's anti-inflammatory and anti-scarring activity. In animal models it reduced fibrosis in the heart, kidney and lung. ACE breaks it down, so ACE-inhibitor drugs raise its levels.

Why people take it

What studies report

• Reduced fibrosis in heart, kidney and lung models
• Anti-inflammatory effects without the actin-binding activity of the full peptide

Worth knowing: Animal only. It is broken down by ACE, so its levels are already altered by common blood pressure drugs.

Status: Animal and cell research only.

Route

Subcutaneous injection, from reconstituted lyophilised powder

Sequence

Ac-Ser-Asp-Lys-Pro

Formula

C20H33N5O9

Molecular weight

487.5 g/mol

CAS

127103-11-1

Available as

10 mg

Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.