Thymosin-β4
Healing & repair In trials Human trials
Also called Tβ4, Timbetasin, often sold as TB-500
A 43-amino-acid peptide found in nearly all human cells. It binds actin, the protein cells use to move, which helps repair cells migrate into damaged tissue. Animal studies link it to blood vessel growth, faster wound and corneal healing, and less scarring and inflammation.
Why people take it
What studies report
- Faster corneal and skin wound healing in animals and early eye trials
- Reduced scarring and inflammation after heart injury in animals
- Drives cell migration into damaged tissue
How it works
Regulates actin, the protein cells use to move, which lets repair cells migrate into damaged tissue. Frequently stacked with BPC-157 for severe musculoskeletal injury.
In practice Unapproved use
- Usually run as a loading period followed by less frequent maintenance
- The standard partner to BPC-157 for serious soft-tissue injury
- Favoured for chronic injuries that have stopped responding to physio
Science hasn't caught up: Most people buying 'TB-500' receive a fragment rather than the full 43-amino-acid peptide — the names are used interchangeably in the market but are not the same molecule.
Reported real-world use, not evidence and not a recommendation.
Worth knowing: Dry eye trials showed promise but no approval followed. Sold widely as 'TB-500', often as a different fragment than the full peptide.
Status: Clinical trials for dry eye and skin wounds. Not approved.
- Route
- Subcutaneous injection, from reconstituted lyophilised powder
- Sequence
- Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
- Formula
- C212H350N56O78S
- Molecular weight
- 4963.4 g/mol
- CAS
- 77591-33-4
- Available as
- 10 mg
Educational information only. Nothing here is medical advice, a dosing protocol, or a recommendation to use any compound. Most entries describe substances not approved for human use. Talk to a licensed clinician before acting on anything you read here. How to read these entries.